"When love doesn't work, we hurt. Indeed, “hurt feelings†is a precisely accurate phrase, according to psychologist Naomi Eisenberger of the University of California. Her brain imaging studies show that rejection and exclusion trigger the same circuits in the same part of the brain, the anterior cingulate, as physical pain."
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Source : Sue Johnson, Kenneth Sanderfer (2016). “Created for Connection: The "Hold Me Tight" Guide for Christian Couples”, p.29, Hachette UK
Source : "Ellie Kemper Writes For McSweeney's, Was A High School Student of Jon Hamm's, and Single-Handedly Saved Us From A Too-Serious Season of The Office". Interview with Daniel Riley, www.gq.com. May 20, 2010.